Publications by authors named "Kathrin Krohn"

The aim of the interdisciplinary S2k guideline "Acute infectious gastroenteritis in infants, children and adolescents" is to summarise the current state of knowledge on the clinical presentation, diagnosis, treatment, prevention and hygiene of acute infectious gastroenteritis, including nosocomial gastrointestinal infections, in infants, children and adolescents on the basis of scientific evidence, to evaluate it by expert consensus and to derive practice-relevant recommendations from it. The guideline provides a corridor for action for frequent decisions. It also serves the purpose of evidence-based further education and training and is thus intended to improve the medical care of children with acute gastroenteritis.

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The prevalence of inflammatory bowel diseases (IBD) in children is rising. These complex diseases typically take an unpredictable course with disease flares. This review serves to illustrate the psychosocial consequences and risks of inflammatory bowel diseases in children and adolescents against the background of the essential medical aspects.

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Article Synopsis
  • Partial enteral nutrition (PEN) was studied in pediatric patients with Crohn's disease to see its effects on bone health, growth, and various metabolic and microbial changes over a year.
  • The study involved 41 patients, with 22 receiving PEN and 19 as controls, where results showed no significant improvements in bone quality, but PEN did enhance growth in younger patients.
  • While PEN did not change the overall diversity of gut microbiota, it did lead to specific metabolomic changes, particularly an increase in certain lipids related to the nutritional formula used.
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Purpose Of Review: Lipid emulsions are crucial for providing essential fatty acids and energy in infants and children requiring parenteral nutrition. There is ongoing debate about the optimal composition of lipid emulsions and the optimal timing for introducing lipids to the parenteral nutrition of premature infants in order to enhance the benefits and to minimize the risk of complications.

Recent Findings: Several studies have investigated the effects of early compared with late administration of lipid emulsions.

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Background: Paediatric intensive care patients often require parenteral nutrition (PN). Only very few standard mixtures are available for infants and children. Individual PN solutions need to be compounded manually on the ward, if preparation by the hospital pharmacy is not feasible.

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