Publications by authors named "Kathrin Kaeppler"

Background: The treatment of complex radial head fractures remains controversial with open reduction and internal fixation (ORIF), radial head arthroplasty, and radial head excision being the most common treatment options. While ORIF is the preferred treatment strategy for Mason type II fractures, the optimal treatment of Mason type III fractures is debated. The purpose of this study was to report minimum 10-year outcomes after ORIF of Mason type II and type III radial head fractures.

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Background: Despite technical advancement, elbow ulnar collateral ligament (UCL) reconstruction is a challenging procedure due to the limitations regarding the challenging tunnel placement and potential injury to the ulnar nerve. Furthermore, current techniques for reconstruction and repair are inferior functionally and biomechanically when compared to native UCL tissue. A modified docking technique using a single-tunnel proximal suspensory fixation may reduce complications and potentially provide a technique for UCL reconstruction that is biomechanically superior.

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Thermomechanical combination injuries (TMCIs) are feared for their demanding preclinical and clinical management and bear the risk of high mortality compared to the single injury of a severe burn or multiple trauma. There remains a significant lack of standardized algorithms for diagnostics and therapy of this rare entity. The objective of the present study was to profile TMCI aiming at standardized procedures.

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Background: The treatment of infection-related delayed bone unions is still very challenging for the orthopedic surgeon. The prevalence of such infection-related types of osteitis is high in complex fractures, particularly in open fractures with extensive soft-tissue damage. The aim of this study was to develop a new animal model for delayed union due to osteitis.

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Decoding the psychological dimensions of human odor perception has long been a central issue of olfactory research. Odor scientists as well as fragrance professionals have tried to establish comprehensive standards for the description, measurement, and prediction of odor quality characteristics. As odor percepts could not be linked to a few measurable physicochemical features of odorous compounds or physiological characteristics of the olfactory system, odor qualities have often been assessed by perception-based ratings.

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Article Synopsis
  • Simvastatin was tested for its effects on bone integration using titanium implants in rats, with a focus on its local application from bioactive coatings.
  • The study involved 80 rats and analyzed different implant coatings (uncoated, polymer-only, and simvastatin coated) over a period of 56 days.
  • Results indicated that high doses of simvastatin led to impaired fixation strength, reduced bone formation, and some cases of osteolysis, suggesting that simvastatin may negatively affect implant integration.
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