Acetazolamide therapy for metabolic alkalosis in critically ill pediatric patients.

Objective: Despite a paucity of supporting literature, acetazolamide is commonly used in critically ill children with metabolic alkalosis (elevated plasma bicarbonate [pHco-3] and pH). The objective of this study was to assess the change in 18 hours after initiation of acetazolamide therapy.

Design: Retrospective study.