Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia.

Objective: Fat-soluble vitamin (FSV) deficiency is a well-recognized consequence of cholestatic liver disease and reduced intestinal intraluminal bile acid. We hypothesized that serum bile acid (SBA) would predict biochemical FSV deficiency better than serum total bilirubin (TB) level in infants with biliary atresia.

Methods: Infants enrolled in the Trial of Corticosteroid Therapy in Infants with Biliary Atresia after hepatoportoenterostomy were the subjects of this investigation.

Philip King Brown and Arequipa Sanatorium: early occupational therapy as medical and social experiment.

Historical inquiry enriches occupational therapy practice by identifying enduring values and inspiring future excellence. This study presents for the first time the pioneering life and work of Philip King Brown, a San Francisco physician who used occupation to treat the physical, mental, and social effects of tuberculosis (TB) at Arequipa Sanatorium, the institution he founded in 1911. Through textual analysis of the Arequipa Sanatorium Records, this article evaluates and defends Brown's assertion that his institution was medically and socially experimental.

Laughter, Leininger, and home healthcare.

Home health clinicians provide care for a culturally diverse patient population. According to Leininger's Theory of Culture Care Diversity and Universality (2010), caring is a universal phenomenon that varies based on a patient's cultural beliefs, values, and practices. Humor therapy promotes spontaneous therapeutic patient laughter.

Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy.

Background: It has been hypothesized that reduced axonal transport contributes to the degeneration of neuronal processes in Parkinson's disease (PD). Mitochondria supply the adenosine triphosphate (ATP) needed to support axonal transport and contribute to many other cellular functions essential for the survival of neuronal cells. Furthermore, mitochondria in PD tissues are metabolically and functionally compromised.

Student outcomes in a postprofessional online master's-degree program.

The outcomes of five cohorts of occupational therapists who completed an online postprofessional master's degree program were evaluated. Data on graduates' satisfaction with professional skills and status, contribution of the program to their satisfaction, and engagement in professional activities since graduation were collected using an online survey. Forty-nine of 65 surveys distributed were returned (75% response rate).

Cadherin conformations associated with dimerization and adhesion.

To investigate conformations of C-cadherin associated with functional activity and physiological regulation, we generated monoclonal antibodies (mAbs) that bind differentially to monomeric or dimeric forms. These mAbs recognize conformational epitopes at multiple sites along the C-cadherin ectodomain aside from the well known Trp-2-mediated dimer interface in the N-terminal EC1 domain. Group 1 mAbs, which bind monomer better than dimer and the Trp-2-mutated protein (W2A) better than wild type, recognize epitopes in EC4 or EC5.

Laugh and learn: humor as a teaching strategy in occupational therapy education.

SUMMARY Humor use in education has been studied in fields such as psychology and nursing. Research has demonstrated that effective educational humor needs to be integrated into the topic and used in moderation. Used appropriately, humor can gain attention, facilitate creative thinking and memory, motivate students to attend class, and promote learning outcomes.