Publications by authors named "Kathleen R Flaherty"
Objective: Androgen deprivation therapy (ADT) is a common treatment for prostate cancer (PCa), with increasing numbers of men on ADT for longer. Limited evidence suggests ADT impacts cognition. This study addressed gaps in the literature by focusing on older men with PCa and assessing ADT usage longer than 1 year.
View Article and Find Full Text PDFBackground: To examine associations between exercise and cognitive function in older men undergoing hormone therapy for prostate cancer.
Method: Men ≥ 65 years old with prostate cancer, currently undergoing androgen deprivation therapy for ≥ 6 months (n = 50), completed the Godin-Shephard Leisure-Time Physical Activity Questionnaire, and standard neuropsychological tests. Pearson's correlations and linear regressions were used to examine associations between exercise and cognitive performance.
Article Synopsis
- The study assessed trends in using technetium Tc 99m pyrophosphate (Tc-PYP) scanning for diagnosing amyloid transthyretin cardiac amyloidosis (ATTR-CA), focusing on patient assessments and diagnostic accuracy.
- It found that while Tc-PYP scanning rates increased, proper monoclonal protein and genetic testing were often lacking among patients, which is crucial for effective diagnosis.
- The results indicated that while Tc-PYP scans showed good sensitivity and specificity, the combination of SPECT and planar imaging was important, as planar imaging had a high rate of false positives in certain cases.
Background: Clinically evident cardiac involvement has been documented in 5% of sarcoidosis patients, primarily manifesting as heart block, ventricular arrhythmias, and heart failure. Heart Rhythm Society consensus guidelines recommend advanced cardiac imaging with fluorodeoxyglucose-positron emission tomography (FDG-PET) scan for diagnosis of cardiac sarcoidosis, given endomyocardial biopsy's low sensitivity.
Case Summary: We describe four patients with cardiac sarcoidosis diagnosed with FDG-PET scan performed using a standardized imaging protocol for cardiac sarcoidosis.
Background: Transthyretin cardiac amyloidosis (ATTR) is a rare, but underdiagnosed, cardiomyopathy. Traditionally diagnosed invasively, ATTR can be diagnosed with non-invasive Technetium pyrophosphate (Tc-PYP) planar scintigraphy. Non-planar imaging has not been validated for ATTR diagnosis.
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