Publications by authors named "Kathleen O Rose"

Article Synopsis
  • There was a significant rise in emergency department visits and hospitalizations for unsupervised medication exposures in young children (<5 years) in the early 2000s, prompting prevention strategies.* -
  • Analyzing data from 2009 to 2020 revealed approximately 678,000 emergency visits, mostly involving children aged 1-2 and prescription solid medications, but there were notable decreases for certain substances like benzodiazepines and opioids.* -
  • Overall, emergency department visits and hospitalizations for these incidents decreased from 66,416 in 2009 to 36,564 in 2020, indicating that prevention efforts have been effective in reducing unsupervised medication exposures.*
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Introduction: Characterization of emergency department visits attributed to adverse events involving benzodiazepines can be used to guide preventive interventions. This study describes U.S.

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Objectives: To estimate the number of US emergency department visits for prescription opioid harms by patient characteristics, intent, clinical manifestations, and active ingredient.

Methods: We used data from medical record-based surveillance from a nationally representative 60-hospital sample.

Results: Based on 7769 cases, there were 267 020 estimated emergency department visits annually (95% confidence interval [CI] = 209 833, 324 206) for prescription opioid harms from 2016 to 2017.

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Introduction: National data on morbidity from nonmedical use of pharmaceuticals are limited. This study used nationally representative, public health surveillance data to characterize U.S.

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Importance: The Patient Protection and Affordable Care Act of 2010 brought attention to adverse drug events in national patient safety efforts. Updated, detailed, nationally representative data describing adverse drug events can help focus these efforts.

Objective: To describe the characteristics of emergency department (ED) visits for adverse drug events in the United States in 2013-2014 and describe changes in ED visits for adverse drug events since 2005-2006.

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Objective: To reduce dosing errors when administering orally ingested over-the-counter liquid medications, the US Food and Drug Administration (FDA) and the Consumer Healthcare Products Association released voluntary recommendations for dosing directions and dosing devices. This study assessed recommendation adherence for national brand name orally ingested over-the-counter liquid pediatric analgesics/antipyretics and cough, cold, and allergy medications available after the FDA guidance was finalized in 2011 to identify and prioritize specific improvements to dosing directions and devices.

Methods: Recommendations were categorized as top tier or low tier based on potential to directly address ≥3-fold dosing errors.

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Objective: To assess whether adding flow restrictors (FRs) to liquid medicine bottles can provide additional protection against unsupervised medication ingestions by young children, even when the child-resistant closure is not fully secured.

Study Design: In April and May 2012, we conducted a block randomized trial with a convenience sample of 110 3- and 4-year-old children from 5 local preschools. Participants attempted to remove test liquid from an uncapped bottle with an FR and a control bottle without an FR (with either no cap or an incompletely closed cap).

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