Publications by authors named "Kathleen Kubes"

Article Synopsis
  • The study aimed to assess if human fibrinogen concentrate could lower blood loss and the need for blood component therapy in neonate and infant patients undergoing cardiac surgery.
  • In a randomized trial with 30 pediatric patients, those receiving fibrinogen concentrate required significantly less cryoprecipitate than the placebo group.
  • While the treatment reduced cryoprecipitate use, it did not significantly affect overall blood loss or other measures of hemostasis and safety compared to the placebo.
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Introduction: Rotational thromboelastometry (ROTEM) has been shown to reduce the need for transfused blood products in adult and pediatric cardiac surgery patients. However, similar evidence in newborns, neonates, and young infants is lacking. We quantified ROTEM value changes in pediatric patients on cardiopulmonary bypass (CPB) before, during and after blood product transfusion.

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This study evaluated whether rotational thromboelastometry (ROTEM; Tem International GmbH, Munich, Germany) FIBTEM maximum clot firmness (MCF) can be used to predict plasma fibrinogen level in pediatric patients undergoing cardiac surgery. Linear regression was conducted to predict plasma fibrinogen level using FIBTEM MCF (0.05 level of significance).

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Background: The aim of this study was to compare three different blood washing techniques and describe the differences for the composition of the washed red blood cells (RBC).

Methods: Stored RBCs less than 5 days old were washed using three different techniques. 1) Washing with normal saline with the COBE Model 2991 blood processor in the blood bank (BB-S).

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