Amplification of Herpes simplex type 1 and Human Herpes type 5 viral DNA from formalin-fixed Alzheimer brain tissue.

It is known that nucleic acids from formalin-fixed tissues are not nearly as good templates for DNA amplification as those extracted from fresh tissues. However, specimens stored in most pathologic archives are initially fixed in formalin. The possibility of an infectious etiology of several diseases including Alzheimer's underscores the usefulness of archived tissue in assessing the association of infectious agents with specific pathology.

Late-developing cerebral arteropathy after pyogenic meningitis.

Background: Although vasculopathy is a recognized complication during acute meningitis, to our knowledge, no previous reports have been published of this phenomenon developing months after successful treatment.

Objective: To report a unique case of a late-developing vasculopathy after pyogenic meningitis in an adult.

Report Of A Case: A 51-year-old woman was seen with severe headache 2 months after treatment of Haemophilus influenzae type C meningitis.