Pilot Randomized Controlled Trial of an Educational Video for CAR T-Cell Therapy Recipients.

Background: CAR T-cell therapy has transformed the treatment of hematologic malignancies, but it is complex and challenging to convey to patients. Educational video interventions are efficacious for improving patient knowledge about cancer therapeutics and informing their care preferences, yet no educational videos have been evaluated in CAR T-cell therapy.

Methods: We conducted a randomized controlled trial comparing an educational video versus usual care in adults (age ≥18 years) with hematologic malignancies receiving CAR T-cell therapy at Massachusetts General Hospital.

Childhood attention deficit hyperactivity disorder, substance use, and adult functioning among incarcerated women.

Objective: To estimate prevalence of childhood ADHD among incarcerated women and determine its association with substance use and adult functioning.

Method: 192 female participants are recruited from the Department of Corrections in Rhode Island. Childhood ADHD is defined as scoring >46 on the Wender Utah Rating Scale.