Publications by authors named "Kathleen Corrado"
We report a large compilation of the internal validations of the probabilistic genotyping software STRmix™. Thirty one laboratories contributed data resulting in 2825 mixtures comprising three to six donors and a wide range of multiplex, equipment, mixture proportions and templates. Previously reported trends in the LR were confirmed including less discriminatory LRs occurring both for donors and non-donors at low template (for the donor in question) and at high contributor number.
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- The GAB1 gene is crucial for cellular morphogenesis and encodes a protein located in the endoplasmic reticulum (ER).
- A temperature-sensitive mutant of GAB1 shows abnormal accumulation of GPI precursors, with its temperature sensitivity being strongly affected by varying levels of GPI transamidase subunits.
- Gab1p and Gpi17p are part of the same protein complex and their depletion affects the ER network and actin cytoskeleton, indicating an important relationship between these cellular structures.