Publications by authors named "Kathleen Cathcart"

Article Synopsis
  • - The study is a retrospective analysis aimed at determining how effective spine MRI is in detecting cancer-related issues in patients experiencing back pain, with a focus on the area scanned (regional vs. total spine).
  • - Results showed that over half of the spine MRIs conducted on cancer patients revealed at least one cancer-related finding, with malignant osseous disease being the most common; total spine MRIs were notably more effective than regional ones in identifying these issues.
  • - The study concludes that using total spine imaging for cancer patients with back pain significantly improves the likelihood of uncovering malignancies, indicating the importance of comprehensive imaging for accurate diagnosis.
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A tumor-specific, bcr-abl-derived fusion peptide vaccine can be safely administered to patients with chronic myelogenous leukemia (CML) and can elicit a bcr-abl peptide-specific T-cell immune response. In the present phase 2 trial, 14 patients with CML in chronic phase were vaccinated with 6 fusion peptides mixed with Quillaja saponaria (QS-21). No significant toxic effects were observed.

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Background: Pulmonary aspergillosis and other invasive fungal infections (IFIs) commonly complicate the management of patients with acute leukemia. Standard amphotericin-based therapies may be ineffective for many patients and the available salvage agents (itraconazole and caspofungin) are reported to possess only moderate activity against resistant infections. Laboratory evidence suggests a synergistic interaction between amphotericin and caspofungin.

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