Objective: This open-label, 24-week study was conducted to evaluate the safety and efficacy of abatacept in patients with refractory juvenile dermatomyositis (DM).
Methods: Ten patients ≥7 years of age with moderate disease activity were enrolled in a 24-week study to examine the safety of subcutaneous abatacept and patient responses to the treatment. The primary endpoint was the International Myositis Assessment and Clinical Studies (IMACS) group Definition Of Improvement (DOI).
J Orthop Sports Phys Ther
March 2017
A 51-year-old man presented to an urgent care facility 2 weeks after onset of left lateral hip and buttock pain. Radiographs were noncontributory. An orthopaedist referred him to physical therapy, but due to the worsening clinical presentation, he was referred back to the orthopaedist for additional evaluation.
View Article and Find Full Text PDFJ Trauma Acute Care Surg
July 2014
Background: The inferior vena cava (IVC) collapses with shock but may also be collapsed in volume-depleted patients in the absence of shock. The speed and availability of computed tomography (CT) make IVC measurement an attractive diagnostic modality for shock. The purpose of this study was to determine if IVC size following injury is associated with shock.
View Article and Find Full Text PDFWe report a case of a migrated Essure permanent birth control device. The correct diagnosis was made on conventional two-dimensional and three-dimensional pelvic sonography 7 years after placement of the device when the patient presented with persistent right-sided pain. The 3-month post placement hysterosalpingogram had shown an appropriately occluded right fallopian tube but had overlooked the abnormal position of the right Essure device, which was too proximal and extending slightly in the uterine cavity.
View Article and Find Full Text PDFBackground: Needle thoracostomy is the emergent treatment for tension pneumothorax. This procedure is commonly done using a 4.5cm catheter, and the optimal site for chest wall puncture is controversial.
View Article and Find Full Text PDFThe intrauterine contraceptive device (IUD) is one of the most widely used reversible contraception methods throughout the world. With advancing technology, it has rapidly gained acceptance through its increased effectiveness and practicality compared with more invasive means such as laparoscopic tubal ligation. This pictorial essay will present the IUDs most commonly used today.
View Article and Find Full Text PDFThis article will describe the different variants of the unicornuate uterus, their clinical presentation and imaging findings, as well their associated complications. We will also review the associated renal anomalies. Patients' symptoms and their imaging findings will vary depending on the unicornuate subtype.
View Article and Find Full Text PDFObjective: The purpose of this pictorial essay is to review the imaging findings of normally and abnormally positioned Essure permanent birth control devices across the different imaging techniques and to show common sites of device migration.
Conclusion: The Essure device is easily visualized on all imaging techniques, and radiologists should be familiar with its appearance and be able to identify cases of device migration on ultrasound and hysterosalpingography that would suggest malfunction.
A 51-year-old woman presented with moderate knee pain refractory to conservative measures. Radiographs revealed a well-defined, but irregularly-shaped ovoid soft tissue density at the posterior superior aspect of the infrapatellar fat pad of Hoffa. On magnetic resonance imaging, the mass was mildly heterogeneous and had intermediate signal in the proton density series and mixed signal intensity on the T2-weighted images.
View Article and Find Full Text PDFPurpose: To determine the ability of magnetic resonance imaging (MRI) to characterize the stability of osteochondritis dissecans (OCD) fragments in juveniles.
Methods: Twenty-eight consecutive patients underwent surgery for OCD between 2004 and 2008. Of these, 23 patients had adequate preoperative imaging.
The Residency Review Committee of the American Council of Graduate Medical Education has designated abdominal radiology as one of the subspecialty areas required for radiology residency training. Because it spans both gastrointestinal and genitourinary organ systems and multiple modalities, a graduated, integrated abdominal radiology curriculum, which is based on the General Competencies, was developed.
View Article and Find Full Text PDFIdiopathic inflammatory myopathies are chronic diseases clinically characterized by symmetrical proximal muscle weakness. MRI has assumed a major role in the evaluation and management of these conditions. It is sensitive to the presence of inflammation and edema, especially with incorporation of fat suppression sequences, so it is a useful tool for establishing an early diagnosis, for evaluating the extent and number of lesions, and for determining the right site for biopsy.
View Article and Find Full Text PDFAnn N Y Acad Sci
February 2009
The superior soft tissue contrast and multiplanar capability of magnetic resonance imaging has contributed to earlier diagnosis and implementation of effective treatment for a variety of arthropathies. Owing to overlapping clinical signs and symptoms, MRI plays a role in delineating the features and stages of these conditions. With the advent of disease-modifying therapies, it is important to diagnose inflammatory arthropathy as early as possible.
View Article and Find Full Text PDFBone marrow edema syndrome (BMES), also known as transient regional osteoporosis, is a rare and poorly understood disease process. We present a case of an elderly patient with the BMES who had a relapsing and remitting course complicated by a hip fracture which presented the unique and a previously unreported opportunity to examine the bony architecture pathologically. The patient responded well to calcitonin and bisphosphonate therapy after surgical repair of his fracture.
View Article and Find Full Text PDFThe purpose of this study was to document range-of-motion differences and radiographic changes in the dominant shoulder of skeletally immature throwers and to determine how pain associated with throwing may relate to these changes. Seventy-nine male youth baseball players (aged 8-15 years) completed a questionnaire, a shoulder examination, and a series of radiographs to determine physeal changes and humeral retroversion. Radiographs were reviewed and interpreted by a blinded musculoskeletal radiologist.
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