Homocysteine and cognitive function in very elderly nondemented subjects.

Objectives: To examine the association of homocysteine with cognitive functioning in very elderly community-dwelling individuals (80 years or older).

Methods: Two hundred twenty-eight nondemented community-dwelling individuals were assessed with a broad neuropsychological battery. Bloods were drawn to measure homocysteine, serum vitamin B12, and folate levels and APOE genotype.