Publications by authors named "Katherine M Soltys"
Lancet Oncol
February 2020
Article Synopsis
- Patient-reported outcomes (PROs) in cancer trials are important for understanding treatment effects on symptoms and quality of life, but there is no agreed-upon method for analyzing them, which complicates result interpretation.
- A consortium was created to establish recommendations for PRO analysis, focusing on research objectives, appropriate statistical methods, and how to handle missing data.
- This Policy Review outlines these recommendations based on comprehensive literature reviews and collaboration among international experts, and it also discusses future developments in this area.
Clin Trials
December 2018
Article Synopsis
- There is currently a lack of agreement on how to analyze and interpret health-related quality of life and patient-reported outcomes in cancer clinical trials, complicating comparisons and the application of findings in healthcare settings.
- The SISAQOL Consortium was formed to create standardized guidelines for analyzing these outcomes in cancer randomized controlled trials, focusing on key priorities identified through member discussions.
- Their efforts aim to develop clear research objectives, select appropriate statistical methods, and establish best practices for dealing with missing data, with input from a diverse membership that includes patients, regulators, and researchers.
Lancet Oncol
November 2016
Article Synopsis
- Health-related quality of life (HRQOL) measures in cancer trials are crucial for evaluating treatments but face challenges in analysis and comparison across studies.
- The SISAQOL initiative aims to standardize the analysis of HRQOL and patient-reported outcomes to improve clarity and applicability of research findings.
- This project hopes to enhance cancer research, assist in decision-making for patients and providers, improve care delivery, and inform health policy.
