Examining the Impact of Cholecystectomy on Tumor Recurrence in Breast Cancer Patients.

Previous studies have found that bile acids influence the growth of breast cancer cells in vitro, suggesting that naturally occurring bile acids may also influence the growth of human breast cancer cells. Cholecystectomy alters modulation of bile acid metabolites, and therefore postcholecystectomy women could be at an increased risk of cancer development and recurrence. This study examined the breast cancer outcome in women who underwent cholecystectomy as compared to those with intact gallbladder.

Impact of gut permeability on the breast microbiome using a non-human primate model.

We previously demonstrated in non-human primates (NHP) that Mediterranean diet consumption shifted the proportional abundance of in the breast and gut. This data highlights a potential link about gut-breast microbiome interconnectivity. To address this question, we compared bacterial populations identified in matched breast and faecal samples from our NHP study.