Resistance training to reduce the malnutrition-inflammation complex syndrome of chronic kidney disease.

Background: Systemic inflammation and protein-energy malnutrition may be associated with poor outcomes in kidney disease.

Methods: We studied 26 adults (age, 65 +/- 10 [SD] years) with chronic kidney disease, not on dialysis therapy. Subjects were randomly assigned to resistance training (n = 14) or a control group (n = 12) for 12 weeks, while counseled to consume a low-protein diet (protein, approximately 0.