Knockdown of Transmembrane Protein 150A () Results in Increased Production of Multiple Cytokines.

Lipopolysaccharide (LPS)-induced signaling through Toll-like receptor 4 (TLR4) is mediated by the plasma membrane lipid, phosphatidylinositol (4,5)-bisphosphate [PI(4,5)P] and its derivatives diacylglycerol and inositol trisphosphate. Levels of PI(4,5)P are controlled enzymatically and fluctuate in LPS-stimulated cells. Recently, transmembrane protein 150A (TMEM150A/TM6P1/damage-regulated autophagy modulator 5) has been shown to regulate PI(4,5)P production at the plasma membrane by modifying the composition of the phosphatidylinositol 4-kinase enzyme complex.

An Assay of Disinfectants on the Viability of Eggs.

Nematodes are widespread and common in poultry. Disinfectants are used to reduce infection rates in poultry houses, but there is little documentation of their effectiveness. An assay was developed to test the efficacy of products to damage eggs, and nine disinfectants and chemicals commonly used in the poultry industry were tested.

, the Cecal Nematode of Gallinaceous Birds: A Critical Review.

is a heavily prevalent poultry parasite that thrives in the ceca of various species of gallinaceous birds. It is a small roundworm, measuring between 4 and 15 mm long, in the family Heterakidae. has a direct life cycle not requiring an intermediate host to complete development, and it is generally believed that poultry raised at high density on litter are at greatest risk for accumulating large numbers of the nematode.

PCR detection of Heterakis gallinarum in environmental samples.

Heterakis gallinarum is a widely distributed cecal nematode that parasitizes gallinaceous birds including chickens and turkeys. H. gallinarum infection poses a problem for the poultry industry as the nematode egg serves as a vector for the protozoan parasite, Histomonas meleagridis, the causative agent of histomonosis.