Publications by authors named "Katherine J Jacoby"
Article Synopsis
- Overdoses of beta-adrenergic and calcium channel antagonists can lead to severe health issues, and treatment options include fluids, calcium salts, and high-dose insulin (HDI).
- A case report discusses a 51-year-old male who overdosed on a combination of amlodipine and metoprolol, requiring HDI and epinephrine to manage life-threatening symptoms, ultimately leading to his recovery.
- The study highlights that after stopping HDI, insulin levels remain elevated for an extended period, suggesting that patients may not need gradual reductions in insulin and often require dextrose supplementation.
Purpose: To determine the etiology and outcomes of critically ill patients with severe hyperammonemia.
Materials And Methods: Retrospective observational study of adults (18 years or older) admitted to a MICU from 2007 to 2016 who had a serum ammonia level >180 μmol/L (3 times the upper limit of normal).
Results: The 78 patients (45 male, 32 female) had a median age of 52 (interquartile range [IQR] 46-58) years.