Publications by authors named "Katherine H Deanna"
Gadoxetate disodium (Gd-EOB-DTPA; gadolinium-ethoxybenzyl-diethylene triamine penta-acetic acid) is a newly developed paramagnetic contrast agent reported to have a high specificity for the hepatobiliary system in humans. The purpose of this prospective study was to describe effects of Gd-EOB-DTPA contrast administration on MRI characteristics of the liver in eight clinically healthy dogs. Precontrast dorsal and transverse T1-weighted spin echo, T2-weighted fast spin echo, and transverse T1-weighted 3D gradient echo (VIBE; volume-interpolated body examination) pulse sequences were acquired for each dog.
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- Motion artifact significantly affects the quality of abdominal MRI in dogs, prompting a study to evaluate how different pulse sequences impact diagnostic quality.
- Ten normal dogs were scanned using 16 MRI pulse sequences, leading to independent scoring of diagnostic quality by four observers and calculations of signal-to-noise and contrast-to-noise ratios.
- The top-performing sequence was dorsal T2 turbo spin echo with fat saturation and breath-holding, while the best overall diagnostic sequence for cranial abdomen featured a combination of techniques that offered short acquisition times and comparable quality, recommended for routine use.