Publications by authors named "Katherine Groble"
Epilepsy Res
September 2012
Article Synopsis
- 2-Deoxy-D-glucose (2DG) is a glucose analog that inhibits glycolysis and shows potential as an anticonvulsant and antiepileptic treatment based on experimental studies.
- The study evaluated 2DG's impact on spatial learning and memory using the Morris water maze and exploratory behavior through the open field test, finding no significant effects on learning and retention but some temporary decreases in exploratory activity at higher doses.
- Overall, 2DG appears to be safe at doses that are effective for seizure control, indicating its promise for future use in epilepsy treatment.
