Oral immunotherapy using weight by volume solutions.

Adapting the subcutaneous immunotherapy methods and schedule for use in oral immunotherapy eases the implementation of oral immunotherapy by simplifying the solution creation process and potentially improves safety with dosing transparency.

The role of hospitals in strengthening primary health care in the Western Pacific.

Despite the imperative to strengthen primary health care (PHC) to respond to demographic and epistemological transitions, and meet commitments to achieve universal health coverage, health systems remain hospital-centric with health resources largely concentrated in urban centres. This paper examines islands of innovation that demonstrate the role hospitals can play in influencing the provision of PHC. Drawing on the literature and country case studies from the Western Pacific region, we illustrate mechanisms used to unlock hospital resources to improve PHC, with the transition towards "systems-focused hospitals".

Universal Health Coverage and the Pacific Islands: An Overview of Senior Leaders' Discussions, Challenges, Priorities and Solutions, 2015-2020.

In 1995, Pacific Health Ministers articulated their vision of a healthy Pacific as 'a place where children are nurtured in body and mind; environments invite learning and leisure; people work and age with dignity; where ecological balance is a source of pride; and where the ocean is protected.' Central to this vision is the achievement of universal health coverage (UHC). To provide an indication of the UHC-related priorities of Pacific health authorities and promote alignment of domestic and international investments in health sector development, we thematically analyzed the discussion, resolutions, and recommendations from 5 years (2015-2020) of senior-level Pacific health meetings.

Role of regulatory capacity in the animal and human health systems in driving response to zoonotic disease outbreaks in the the Mekong region.

We conducted a policy situation analysis in three Mekong region countries, focused on how the animal and human health systems interact to control avian influenza (AI). The study used scoping literature reviews aimed at establishing existing knowledge concerning the regulatory context. We then conducted a series of key informant interviews with national and sub-national government officials and representatives of producers and poultry farmers to understand their realities in managing the complex interface of the two sectors to control AI.

Eliminating again, for the last time: A case study of donor support for malaria in Solomon Islands.

Malaria elimination has been a recurring policy goal in Solomon Islands and has historically succeeded in attracting substantial donor support. Drawing on literature review and key informant interviews, we examine the influence of foreign aid on malaria control and elimination efforts in Solomon Islands between 2002 and 2016, as a unique case study of an Asia-Pacific country with high malaria burden and high donor funding. While aid appears to have contributed to reduced malaria prevalence, the ways in which aid was delivered in the short term had health systems impacts with implications for the elimination agenda.

Food Sublingual Immunotherapy Using Consistent, Cheaper and Customizable Oral Immunotherapy Solutions.

Food SLIT (sublingual immunotherapy) is a food desensitization method with a daily maintenance dose of <10 mg for up to 5 years. Many protocols use commercially available skin test extracts. Oral immunotherapy (OIT) treatment solutions have consistent protein concentrations, are comparatively cheaper and customizable and therefore were adapted for use in a published SLIT dosing schedule.

Implementation Lessons from a Multifaceted National Newborn Program in Solomon Islands: A Mixed-Methods Study.

Multifaceted interventions are important in improving neonatal quality of care and health outcomes. This study describes the implementation of an intervention to improve the quality of newborn care in Solomon Islands, a small island developing state and lower middle-income country in the Western Pacific. Inputs included training, equipment provision, and healthcare system organizational changes.

Sustainable Transition From Donor Grant Financing: What Could It Look Like?

Donor transition is an important aspect of sustaining the impact of donor investments after financial support has ceased. This article compares, contrasts, and critiques the transition policies of the top health donors in the Asia Pacific, which includes Global Fund to fight AIDS, tuberculosis, and malaria, Gavi-the Vaccine Alliance, World Bank (International Development Association), and the United States US Agency for International Development to gain a deeper understanding of what a sustainable financial transition could look like. A literature review of the academic and gray literature was undertaken to ascertain these donors' transition policies and to determine the success of these policies in ensuring sustainable and effective transition.

Achieving UHC in the Pacific, a Closer Look at Implementation: Summary of a Report for Pacific Health Ministers.

The principles of universal health coverage (UHC) are deeply embedded in health systems across the Pacific. UHC is also one of the stepping stones to achieving the Healthy Islands vision, adopted by Pacific health ministers in 1995, which envisages healthy islands as places where citizens grow, learn, play, and age with dignity. However, recent evidence suggests that though health systems across the Pacific largely remain affordable, there are growing challenges in ensuring access to good quality essential services.

What, why and how do health systems learn from one another? Insights from eight low- and middle-income country case studies.

Background: All health systems struggle to meet health needs within constrained resources. This is especially true for low-income countries. It is critical that they can learn from wider contexts in order to improve their performance.

Prehospital Administration of Epinephrine in Pediatric Anaphylaxis - A Statewide Perspective.

Objective: Timely administration of epinephrine is critical in the treatment of anaphylaxis. This study sought to determine the frequency of administration of epinephrine by EMS providers caring for pediatric patients in the prehospital setting.

Methods: We examined data from the NC EMS database (PreMIS) from 2010-3 to determine frequency of epinephrine administration in pediatric patients with anaphylaxis.

Closing the gaps in child health in the Pacific: an achievable goal in the next 20 years.

It is not inconceivable that by 2035 the substantial gaps in child health across the Pacific can close significantly. Currently, Australia and New Zealand have child mortality rates of 5 and 6 per 1000 live births, respectively, while Pacific island developing nations have under 5 mortality rates ranging from 13 to 16 (Vanuatu, Fiji and Tonga) to 47 and 58 per 1000 live births (Kiribati and Papua New Guinea, respectively). However, these Pacific child mortality rates are falling, by an average of 1.

Self-assembly of linear arrays of semiconductor nanoparticles on carbon single-walled nanotubes.

Ligand-stabilized nanocrystals (NCs) were strongly bound to the nanotube surfaces by simple van der Waals forces. Linear arrays of CdSe and InP quantum dots were formed by self-assembly using the grooves in bundles of carbon single-walled nanotubes (SWNTs) as a one-dimensional template. A simple geometrical model explains the ordering in terms of the anisotropic properties of the nanotube surface.