Publications by authors named "Katherine Falloon"

Article Synopsis
  • Inflammatory bowel disease (IBD)-associated spondyloarthritis (SpA) is a common but complex condition that needs better understanding and management strategies.
  • For diagnosing IBD-associated peripheral SpA (IBD-pSpA), collaboration with rheumatology is crucial for evaluating symptoms, physical exams, and imaging.
  • Treatment should start with addressing the underlying IBD activity and may include advanced therapies, with a similar collaborative approach recommended for diagnosing and managing axial SpA (IBD-axSpA), using targeted medications as necessary.
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Background: Inflammatory bowel disease (IBD)-associated peripheral spondyloarthritis (pSpA) decreases quality of life and remains poorly understood. Given the prevalence of this condition and its negative impact, it is surprising that evidence-based disease definitions and diagnostic strategies are lacking. This systematic review summarizes available data to facilitate development and validation of diagnostics, patient-reported outcomes, and imaging indices specific to this condition.

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Background: Cutaneous extra-intestinal manifestations (EIM) occur in up to 20% of patients with IBD. Information about Sweet syndrome (SS)'s clinical course as a rare cutaneous EIM in IBD is limited to case reports. We present the largest retrospective cohort on the occurrence and management of SS in IBD.

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Background: Autoimmune pancreatitis [AIP] is rarely associated with inflammatory bowel disease [IBD]. The long-term outcomes of AIP and IBD in patients with coexisting AIP-IBD and predictors of complicated AIP course have rarely been reported.

Methods: An ECCO COllaborative Network For Exceptionally Rare case reports project [ECCO-CONFER] collected cases of AIP diagnosed in patients with IBD.

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Background: Ileal pouch inflammation is a common problem following ileal pouch-anal anastomosis (IPAA). Despite its prevalence, diagnosis remains multimodal and requires endoscopy. The use of biomarkers in the prediction of and/or association with pouchitis has not been well characterized.

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Granulomatosis with polyangiitis (GPA), previously known as Wegener granulomatosis, is a rare small vessel vasculitis affecting mainly Whites. The prevalence of GPA in the United States is estimated to be 3 of 100,000 individuals. Classically, GPA affects upper airways, lungs, and kidneys, with the upper airways being the most common site.

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Article Synopsis
  • Extra-intestinal manifestations (EIMs) of inflammatory bowel diseases (IBD) are common but lack standardized definitions, diagnostic strategies, and treatment approaches.
  • An interdisciplinary expert panel utilized a modified Delphi consensus to develop definitions and guidelines for diagnosing and managing five major EIMs: erythema nodosum, pyoderma gangrenosum, uveitis, peripheral arthritis, and axial arthritis.
  • The resulting consensus criteria aim to improve clinical practice and guide future research on EIM management through clear diagnostic criteria, specialist identification, and suggested monitoring practices.
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Artificial intelligence [AI] techniques are quickly spreading across medicine as an analytical method to tackle challenging clinical questions. What were previously thought of as highly complex data sources, such as images or free text, are now becoming manageable. Novel analytical methods merge the latest developments in information technology infrastructure with advances in computer science.

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Background & Aims: In patients with acute severe ulcerative colitis (ASUC), standard infliximab induction therapy has modest efficacy. There are limited data on the short-term or long-term efficacy of accelerated infliximab induction therapy for these patients.

Methods: In a retrospective study, we collected data from 213 patients with steroid refractory ASUC who received infliximab rescue therapy at 3 centers, from 2005 through 2017.

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