Publications by authors named "Katherine Doucet"
Article Synopsis
- Amyotrophic Lateral Sclerosis (ALS) involves the loss of motor neurons, which may be linked to changes in synapses related to TDP-43 protein issues.
- The study used advanced microscopy techniques to investigate the presence and distribution of pTDP-43 in excitatory synapses in the spinal cord of mice.
- Findings showed that pTDP-43 is present in about half of spinal cord synapses, primarily concentrated in those connected to VGLUT1 presynaptic terminals, and there was no observable difference in its expression between ALS-afflicted mice and healthy controls.
Background: CARING is a screening tool developed to identify patients who have a high likelihood of death in 1 year.
Aim: This study sought to validate a modified CARING tool (termed PREDICT) using a population of patients presenting to the Emergency Department.
Setting/participants: In total, 1000 patients aged over 55 years who were admitted to hospital via the Emergency Department between January and June 2009 were eligible for inclusion in this study.