Publications by authors named "Katherine Colon Reyes"
Article Synopsis
- HSV-1 primarily infects the oral and nasal areas before establishing latency in the trigeminal ganglion and can also infect the central nervous system (CNS) via specific pathways.
- Recent studies have highlighted the lack of detailed knowledge about which brain regions are affected during HSV-1 infections and how microglial responses differ across these regions.
- This study on a mouse model revealed a two-step spread of HSV-1 from the olfactory epithelium to select brain regions, along with varying activation levels of microglia, contributing to understanding HSV-1's role in neurological diseases.
Article Synopsis
- HSV-1 primarily infects the oral and nasal areas before becoming latent in the trigeminal ganglia and can also infect the central nervous system (CNS) through specific pathways.
- The study used a mouse model to observe how HSV-1 spreads through the olfactory epithelium and CNS, finding a distinct spread pattern and accompanying inflammatory response from immune cells.
- The research identified specific brain regions affected by HSV-1, revealing no involvement of the hippocampus or cortex, and highlighted varied microglial activation across different regions, suggesting implications for neurological diseases.
Background: The morphology of foot joints is widely accepted as a significant factor in the development of various foot disorders. Nevertheless, the role of the first tarsometatarsal joint (TMT1) morphology in hallux valgus (HV) remains unclear, and its impact on TMT1 instability has not been fully explored. This study aimed to investigate the TMT1 morphology and its potential correlation with HV and TMT1 instability.
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