Publications by authors named "Katherine C Matsuda"
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Synopsis of recent research by authors named "Katherine C Matsuda"
- Katherine C Matsuda's research primarily focuses on the pharmacokinetics and pharmacodynamics of therapeutic monoclonal antibodies (mAbs), with particular attention to their interaction with proprotein convertase subtilisin/kexin type 9 (PCSK9), which is relevant for treating cardiovascular diseases.
- A significant portion of her work investigates alternative sample collection methods, specifically the use of dried blood spots (DBS), to measure therapeutic mAb concentrations, which has proven to be a reproducible and effective technique in comparison to traditional serum or plasma analysis methods.
- Matsuda's findings suggest that while affinity-dependent characteristics of mAbs impact their effectiveness in vivo, the advancement of DBS technology for quantifying therapeutic antibodies presents a promising approach for improving clinical pharmacokinetic assessments.
