Publications by authors named "Katherine Begley"
Article Synopsis
- This study aimed to assess the safety, effectiveness, and patient satisfaction of doxycycline sclerotherapy for treating aneurysmal bone cysts (ABCs) and unicameral bone cysts (UBCs).
- A total of 77 lesions were analyzed, with a 99% success rate in treatment and a low recurrence rate, as most patients reported significant pain relief and improved function after treatment.
- Overall, doxycycline sclerotherapy was found to be a safe and effective option for these conditions, with high patient satisfaction, indicating that most patients would choose the treatment again if necessary.
Article Synopsis
- This study evaluated the prevalence of respiratory syncytial virus (RSV) in patients with medically attended acute respiratory illnesses (MAARI) over three seasons, shedding light on its commonality compared to influenza.
- Through the Michigan Ford Influenza Vaccine Effectiveness study, 4,442 participants aged 6 months and older were tested for RSV and influenza, revealing that 9.9% were positive for RSV, particularly common in children aged 6 months to 4 years.
- The findings highlighted that adults with RSV-MAARI had higher multimorbidity indices than those with influenza, emphasizing the need for better awareness and clinical decision-making regarding RSV vaccination strategies, especially in older adults.
Background: Current understanding of severe respiratory syncytial virus (RSV) infections in adults is limited by clinical underrecognition. We compared the prevalence, clinical characteristics, and outcomes of RSV infections vs influenza in adults hospitalized with acute respiratory illnesses (ARIs) in a prospective national surveillance network.
Methods: Hospitalized adults who met a standardized ARI case definition were prospectively enrolled across 3 respiratory seasons from hospitals participating across all sites of the US Hospitalized Adult Influenza Vaccine Effectiveness Network (2016-2019).
Organic semiconductors (OSCs) are promising transducer materials when applied in organic field-effect transistors (OFETs) taking advantage of their electrical properties which highly depend on the morphology of the semiconducting film. In this work, the effects of OSC thickness (ranging from 5 to 15 nm) on the piezoresistive sensitivity of a high-performance p-type organic semiconductor, namely dinaphtho [2,3-b:2,3-f] thieno [3,2-b] thiophene (DNTT), were investigated. Critical thickness of 6 nm thin film DNTT, thickness corresponding to the appearance of charge carrier percolation paths in the material, was demonstrated to be highly sensitive to mechanical strain.
View Article and Find Full Text PDFBackground: Sialorrhea is common in children with neurological disorders and leads to social isolation, aspiration pneumonia and increased caregiver burden. Sialorrhea management includes anticholinergic medications and a variety of surgeries, but these are limited by side effects, recurrence and risks.
Objective: We present our method of salivary gland ablation, an interventional radiology treatment for sialorrhea, and report safety and efficacy data from pediatric patients who underwent salivary gland ablation.
Article Synopsis
- Current acellular pertussis vaccines are ineffective against the pathogen, leading to a rise in cases of a once-controlled disease.
- This study investigates the use of intranasal (IN) immunization with DTaP, especially when combined with curdlan, to mimic natural mucosal immunity and improve vaccine responsiveness.
- Results showed that IN delivery of DTaP led to effective localized immune responses in the lungs and nasal regions, resulting in protective effects against infection and reduced inflammation compared to traditional injection methods.