Goals of Care Discussion Characteristics and Disparities in Children With Medical Complexity.

Objective: Children with medical complexity (CMC) have disproportionately high health care utilization and mortality. Goals of care (GOC) discussions improve goal concordance and subjective outcomes for CMC and their caregivers; however, little is known about the frequency or characteristics of GOC discussions in CMC. We sought to define GOC discussion frequency and attributes in CMC and identify patient characteristics that may influence GOC discussion occurrence.

Cerebrospinal Fluid Composition of Infants with Ischemic Stroke.

Objective:  This study aimed to characterize the cerebrospinal fluid (CSF) of infants with stroke and compare those findings to the CSF of infants with bacterial meningitis and neither condition in the first 14 postnatal days.

Study Design:  Cohort study of 30,092 infants who received a lumbar puncture in the first 14 postnatal days discharged from >400 neonatal intensive care units from 1997 to 2020. CSF parameters were compared between infants with stroke and bacterial meningitis using non-parametric hypothesis testing and quantile regression.