Publications by authors named "Katherine Amy Lin"
Background: Prior studies have noted gender differences in cognition, imaging, and pathological markers in mild cognitive impairment (MCI) subjects. Sex hormone-binding globulin (SHBG), a major controlling factor in the proportion of bioavailable versus bound testosterone and estrogen, has been proposed to contribute to links between hormones and dementia, but has not yet been investigated fully in a prospective biomarker trial.
Objective: This study examined whether, among subjects with MCI, SHBG levels predict future rate of cognitive decline.