Publications by authors named "Katherine A E Hurley"
Effect of calf age and administration route of initial multivalent modified-live virus vaccine on humoral and cell-mediated immune responses following subsequent administration of a booster vaccination at weaning in beef calves.
Am J Vet Res
February 2013
Objective: To compare immune responses following modified-live virus (MLV) vaccination at weaning after intranasal or SC administration of an MLV vaccine to beef calves at 2 or 70 days of age.
Animals: 184 calves.
Procedures: Calves were allocated to 1 of 5 groups.
Article Synopsis
- - The study aimed to assess the effects of black walnut extract (BWE) on immune cells from horses, focusing on any proinflammatory properties it may have.
- - Researchers processed BWE to ensure it was free of contaminants, then tested how different concentrations affected the activity and viability of horse mononuclear cells, looking at factors like cell death and inflammatory markers.
- - Results showed that while BWE did not damage cell membranes, it increased certain inflammatory activities in a dose-dependent manner and could work alongside LPS to contribute to inflammation-related conditions like acute laminitis in horses.
Objective: To assess the in vitro capability of aqueous black walnut extracts (BWEs) to generate reactive oxygen species in water-based media ranging in makeup from a simple buffer solution to a complex solution containing serum.
Sample: 3 BWEs.
Procedures: Production of reactive oxygen species by BWEs prepared in water or N-hexane was tested in PBS solution, PBS solution containing 0.
Objective: To evaluate the use of a commercially available 5-carboxyfluorescein-based, intramolecularly quenched, fluorescence resonance energy transfer (FRET) peptide substrate of renin for measurement of plasma renin concentration in cats.
Sample Population: Plasma samples obtained during a previous study of renal autograft ischemia-reperfusion injury in 10 cats and samples of fetal bovine serum containing recombinant human renin (rh-renin).
Procedures: Experiments involving samples of fetal bovine serum containing rh-renin were conducted to identify a suitable control vehicle, optimal substrate concentration, and appropriate duration of incubation.