Publications by authors named "Katharina Wolters"
Article Synopsis
- Fibrosis, marked by excessive extracellular matrix formation, disrupts tissue function, with Y-box binding protein-1 (YB-1) being a key regulator in this process.
- * The study investigates the role of YB-1 in chronic kidney diseases and acute injury models, using methods like transcriptome analysis and histopathological staining to understand its influence on fibrogenic pathways.
- * Findings indicate that YB-1 regulates important fibrogenic signatures, affecting genes like Klotho, and suggests that targeting YB-1 could offer new avenues for epigenetic therapies to combat fibrosis.*
Gelatin-based hemostats have been used in various surgical fields and showed advantageous effects on central aspects of wound healing when compared to cellulose-based hemostats. Nevertheless, the influence of gelatin-based hemostats on wound healing has not been fully explored yet. Hemostats were applied to fibroblast cell cultures for 5, 30, 60 min, 24 h, 7 and 14 days and measurements were taken at 3, 6, 12, 24 h and 7 or 14 days, respectively.
View Article and Find Full Text PDFHigh salt diet (HSD) is a hallmark of blood pressure elevations, weight gain and diabetes onset in the metabolic syndrome. In kidney, compensatory mechanisms are activated to balance salt turnover and maintain homeostasis. Data on the long-term effects of HSD with respect to tubular cell functions and kidney architecture that exclude confounding indirect blood pressure effects are scarce.
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