4K 3-dimensional video microscope system (orbeye) for transsphenoidal pituitary surgery.

Background: In previous reports on experiences with an exoscope, this new technology was not found to be applicable for transsphenoidal pituitary surgery. As a specialized center for pituitary surgery, we were using a 4K 3D video microscope (Orbeye, Olympus) to evaluate the system for its use in transsphenoidal pituitary surgery in comparison to conventional microscopy.

Method: We report on 296 cases performed with the Orbeye at a single institution.

Bevacizumab in Aggressive Pituitary Adenomas - Experience with 3 Patients.

Objective: To investigate bevacizumab as alternative treatment of aggressive pituitary adenomas after exhaustion of standard therapies.

Design And Methods: Retrospectively, 3 patients undergoing microscopic transsphenoidal surgery of aggressive pituitary adenomas from 2008 till 2018 that were treated with bevacizumab were identified. Development of disease and treatment were evaluated.

Symptomatic Vasospasms as a Life-Threatening Complication After Transsphenoidal Surgery.

Objective: To identify symptomatic vasospasms as a rare complication after transsphenoidal surgery, with emphasis on management and outcomes.

Methods: In this retrospective study, the medical records of 1997 patients who underwent microscopic transsphenoidal surgery at our hospital between 2008 and 2016 were analyzed regarding postoperative vasospasm events, clinical management, and neurologic outcomes.

Results: Four patients (0.