Publications by authors named "Katharina Kreymborg"
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Synopsis of recent research by authors named "Katharina Kreymborg"
- Katharina Kreymborg's research primarily focuses on the roles of various immune cells and regulatory molecules in both adaptive and innate immunity, particularly examining the mechanisms behind effector differentiation in innate lymphoid cells (ILCs) and the implications of costimulatory molecules like B7-H3 and B7-H4 in graft-versus-host disease (GVHD) and cancer.
- Notable findings include the identification of early differentiation stages in T-bet ILC1s driven by Hobit, as well as the significant negative regulatory roles of B7-H4 and B7-H3 in acute GVHD lethality, suggesting targeted therapeutic potentials in these pathways.
- Additionally, Kreymborg's work highlights the dual roles of cytokines such as IL-22 in both promoting and limiting inflammation depending on the tissue context and disease model, as well as the contribution of Th17 lymphocytes to central nervous system inflammation and blood-brain barrier disruption.
