Publications by authors named "Katharina Bohne"

Background: Pancreatic polypeptide is released immediately after food ingestion. The release is operated by vagal-abdominal projections and has therefore been suggested as a test for vagal nerve integrity. Pathoanatomical and clinical studies indicate vagal dysfunction in early Parkinson's disease (PD).

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Background: Delayed gastric emptying is a non-motor symptom of Parkinson's disease. Few data exist on gastric emptying in early-stage Parkinson's disease. In idiopathic rapid-eye-movement sleep behavior disorder, a presumable pre-motor stage of Parkinson's disease, gastric emptying has not yet been investigated.

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Article Synopsis
  • Ghrelin is an orexigenic peptide that affects gut movement and brain functions; it may have protective effects in Parkinson's disease (PD).
  • Research shows that PD patients and those with idiopathic REM sleep behavior disorder (iRBD) have altered responses in ghrelin levels post-meal compared to healthy individuals.
  • Reduced ghrelin secretion in these patients could indicate a risk for neuron damage and may serve as a potential biomarker for diagnosis or treatment of PD.
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