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Publications by authors named "Kateryna Potapenko"

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inhibited the growth of primary liver cancer by inducing early apoptosis and senescence, .
Oladimeji Paul Duduyemi Kateryna Potapenko Nataliia Limanska Sofiya Kotsyuda Nataliia Petriv

Front Microbiol

November 2024

Article Synopsis
  • Primary liver cancer (PLC), including hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), has a high mortality rate and current treatments are limited with severe side effects, highlighting the need for new therapies.
  • The study investigates the anticancer effects of two Lactobacilli strains (Lp 12 and Lp 355), derived from grapes, and compares them to the well-studied strain (Lc 393) on PLC cell lines, testing them in various forms and combinations with standard chemotherapy.
  • Results indicate that both live suspensions and sonicated extracts of the Lactobacilli strains significantly inhibited PLC cell growth and showed synergistic effects when combined with chemotherapeutics, allowing for lower doses
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