The modern view of the use of extracorporeal detoxification in the treatment of drug poisoning (overdose).

Objective: Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..

Patients And Methods: Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020.

The essence of students' vitality in the context of its reflexive determination.

Objective: Aim: Theoretical analysis of the problem of the individual's vitality in the context of its reflective determination, an empirical study of the formation of its components, and the proof of correlations with various types of reflection.

Patients And Methods: Materials and Methods: The following psychodiagnostic methods were used in the empirical study: "Methodology of vitality diagnosis" by S. Maddi in an adaptation by D.

Glutathione-S-transferases genes-promising predictors of hepatic dysfunction.

One of the most commonly known genes involved in chronic diffuse liver diseases pathogenesis are genes that encodes the synthesis of glutathione-S-transferase (GST), known as the second phase enzyme detoxification system that protects against endogenous oxidative stress and exogenous toxins, through catalisation of glutathione sulfuric groups conjugation and decontamination of lipid and deoxyribonucleic acid oxidation products. The group of GST enzymes consists of cytosolic, mitochondrial and microsomal fractions. Recently, eight classes of soluble cytoplasmic isoforms of GST enzymes are widely known: α-, ζ-, θ-, κ-, μ-, π-, σ-, and ω-.

Innovative and interactive teaching methods as a means of optimizing the educational process of higher medical education.

Objective: Introduction: The public need prompts the modern school to find new ideas and technologies, to share and adopt the advanced pedagogical experience. Achieving the ultimate goal of the educational process in universities is training of highly qualified and competitive specialists in health care. The aim of the study is to assess the results of using the innovative and interactive teaching methods implemented in the national system of higher medical education.