Publications by authors named "Katerina Ohui"
Article Synopsis
- The study investigates copper(II) thiosemicarbazone complexes as potential anticancer agents, targeting both ribonucleotide reductase (RNR) and tubulin polymerization.
- The researchers synthesized and characterized four proligands with a methylmorpholine substituent, noting how the position of this group influences the complexes' efficacy against cancer cells.
- Findings indicate that the complexes effectively inhibit key cancer-related processes, with their antiproliferative activity tied to mechanisms that quench a radical in RNR and impede tubulin polymerization.
