Publications by authors named "Katelyn Neuman"

Article Synopsis
  • - The study explores how axonal growth can be influenced by both the physical environment, such as magnetic fields and materials, and the genetic mechanisms involved, using a new ferromagnetic composite material called glass-coated magnetic microwire.
  • - Researchers cultured rat dorsal root ganglia (DRG) under different conditions to analyze neurite outgrowth, discovering that combining magnetic stimulation with the microwire significantly increased both total neurite growth and directed growth compared to control conditions.
  • - RNA sequencing showed that the combination of the magnetic field and microwire reduced the expression of certain immune-response-related genes, hinting at how physical stimulation could guide axon growth and improve our understanding of tissue interactions.
View Article and Find Full Text PDF

Over the past two decades, electrospinning has emerged as a common technique to produce biomedical scaffolds composed of ultrafine fibers formed from many natural and synthetic polymers. A major advantage of this technique is the ability to produce scaffolds that resemble the native extracellular matrix in physical, chemical, and topological properties. However, scaffolds fabricated via electrospinning are not formed with a controlled architecture and typically do a poor job of directing cell growth into prescribed structures for tissue/organ development.

View Article and Find Full Text PDF

. Regeneration of damaged nerves is required for recovery following nervous system injury. While neural cell behavior may be modified by neuromodulation techniques, the impact of static direct current (DC) magnetic stimulation remains unclear.

View Article and Find Full Text PDF

The field of tissue engineering has benefited greatly from the broad development of natural and synthetic polymers. Extensive work in neural engineering has demonstrated the value of conductive materials to improve spontaneous neuron activity as well as lowering the necessary field parameters for exogenous electrical stimulation. Further, cell fate is directly coupled to the mechanical properties of the cell culture substrate.

View Article and Find Full Text PDF