Publications by authors named "Katelyn M Davis"
Prolonged heat and sea salt aerosols pose a challenge for the mammalian airway, placing the protective airway surface liquid (ASL) at risk for desiccation. Thus, mammals inhabiting salt marshes might have acquired adaptations for ASL regulation. We studied the airways of the rice rat, a rodent that inhabits salt marshes.
View Article and Find Full Text PDFSex-specific airway hyperreactivity and sex-specific transcriptome remodeling in neonatal piglets challenged with intra-airway acid.
Am J Physiol Lung Cell Mol Physiol
January 2019
Article Synopsis
- Acute airway acidification triggers sensory nerve responses and is linked to conditions like asthma and gastroesophageal reflux disease in both infants and adults.
- The study examined the gene expression changes in airway-nervous system circuits of neonatal piglets exposed to intra-airway acid, revealing sex-specific responses to this acidification.
- Male piglets showed heightened airway reactivity and obstruction, while females only exhibited obstruction, suggesting different underlying molecular mechanisms in how asthma-like symptoms manifest.