The hybrid nanocomposite materials based on the vermiculite/zinc oxide-chlorhexidine were prepared in two steps. In the first step the vermiculite/zinc oxide nanocomposite was prepared by the mechanochemical method followed by a heat treatment at 650 °C for 90 min. In the second step the chlorhexidine dihydrochloride was intercalated to the vermiculite/zinc oxide nanocomposite in weight ratio 1:1, 1:2, 1:4, 2:1 and 4:1 (wt%) thereby vermiculite/zinc oxide-chlorhexidine nanocomposites were prepared.
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