The Tuberous Sclerosis 2000 Study: presentation, initial assessments and implications for diagnosis and management.

Aims: The Tuberous Sclerosis 2000 Study is the first comprehensive longitudinal study of tuberous sclerosis (TS) and aims to identify factors that determine prognosis. Mode of presentation and findings at initial assessments are reported here.

Methods: Children aged 0-16 years newly diagnosed with TS in the UK were evaluated.