Case report: Disseminated intravascular coagulation in a dog following treatment with melarsomine for .

Disseminated intravascular coagulation following melarsomine therapy for is reported in a 9-year-old female intact pit bull-type dog. The dog had been diagnosed with (antigen and microfilaria positive) and treated with imidacloprid, moxidectin, doxycycline and 3 doses of melarsomine over a 92-day period. Seven days after the third melarsomine injection, the patient was presented to her family veterinarian due to right pelvic limb swelling.

Prevalence of dog erythrocyte antigen 1 in a population of dogs tested in California.

Background: Multiple studies have evaluated the breed-specific prevalence of dog erythrocyte antigen (DEA) 1 in various geographic regions. However, few large-scale studies exist that describe breed prevalence of DEA 1 in the United States.

Key Findings: From January 2000 to October 2020, 6469 dogs had their RBC antigen type determined and were included in the study.

Manual plasma exchange to treat an accidental overdose of intravenous lipid emulsion in a dog with baclofen toxicosis.

Case Description: An approximately 2-year-old sexually intact male German Shorthair Pointer was presented for treatment of baclofen toxicosis.

Clinical Findings: The dog had signs of severe baclofen toxicosis (no gag reflex, intermittent vocalization, and stupor) and received intravenous lipid emulsion (142 mL/kg) as a constant rate infusion over 11 hours. Severe hypertriglyceridemia (29,221 mg/dL; reference interval, 19 to 133 mg/dL) developed, followed by cardiovascular depression (poor peripheral perfusion, hyperlactatemia, and hypertension), severe hypoglycemia (26 mg/dL), acute kidney injury (serum creatinine, 3.

Gastrointestinal obstruction secondary to activated charcoal granule impaction in a dog.

Objective: To describe a serious adverse event of gastrointestinal obstruction requiring surgery following routine administration of multiple doses of activated charcoal (AC) granules, which were prescribed for carprofen toxicosis.

Case Summary: A 2-year-old female neutered Airedale Terrier presented for ingestion of 207 mg/kg of carprofen. Decontamination was initiated with apomorphine to induce emesis.

Evaluation of pulse oximetry as a surrogate for PaO in awake dogs breathing room air and anesthetized dogs on mechanical ventilation.

Objective: To evaluate the ability of arterial hemoglobin oxygen saturation measurement via pulse oximetry (SpO ) to serve as a surrogate for PaO in dogs.

Design: Two-part study: prospective observational and retrospective components.

Setting: University teaching hospital.

Severe hypernatremia and transient azotemia in a cat following inadvertent intravenous administration of a commercial polyethylene glycol solution.

Objective: To describe the clinical signs, clinicopathologic abnormalities, treatment, and outcome after IV administration of polyethylene glycol 3350 (PEG3350) in a cat.

Case Summary: A cat was inadvertently administered 6 g/kg of PEG3350 in electrolyte solution, IV, resulting in severe hypernatremia (203 mmol/L), diffuse encephalopathy, hemolysis, and moderate azotemia. The hemolysis and acute kidney injury observed immediately following PEG3350 administration resolved with supportive care.

Validation of a smartphone-based point-of-care hemoglobin assay for use in dogs.

Objective: To validate a smartphone-based spectrophotometric assay for point-of-care (POC) measurement of hemoglobin (Hgb) concentration against the standard measurement method in dogs without increases in serum lipemia, hemolysis, or bilirubin.

Design: Prospective observational study.

Setting: University teaching hospital.

Does price transparency legislation allow the uninsured to shop for care?

Background: The majority of states have enacted price transparency laws to allow patients to shop for care and to prevent price discrimination of the uninsured. In California, hospitals must provide a price estimate to a requesting uninsured patient and cannot bill for an amount greater than the reimbursement the hospital would receive from a government payer.

Objective: To assess the response rate of California hospitals to a patient price request and to compare the price estimates received to Medicare reimbursement.