Aims: The aim of this study was to establish the pharmacokinetic profile of serum oestriol (E ) concentrations over 24 h following application of vaginal E in chronic users (>12 weeks of E use). The interindividual and intraindividual differences before and after E were examined.
Methods: Ten women participated.
Am J Physiol Regul Integr Comp Physiol
May 2017
ATP release from urinary bladder is vital for afferent signaling. The aims of this study were to localize calcium homeostasis modulator 1 (CALHM1) and pannexin-1 expression and to determine their involvement in mediating ATP release in the bladder. To determine gene expression and cellular distribution, PCR and immunohistochemistry were performed, respectively, in the porcine bladder.
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