Alexander Bain's Mind and Body (1872): An underappreciated contribution to early neuropsychology.

Alexander Bain (1818-1903) is well known for his two influential textbooks, The senses and the intellect (1855) and The emotions and the will (1859). In comparison, Bain's Mind and body: The theories of their relation (1872) has been of limited interest to historians, and it is here where he presents one of the first neural network models. This paper addresses the historical foundations of Bain's neural network model and explores some of his primary influences.

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes.

RIC-3 enhances the functional expression of certain nicotinic acetylcholine receptors (nAChRs) in vertebrates and invertebrates and increases the availability of functional receptors in cultured cells and Xenopus laevis oocytes. Maximal activity of RIC-3 may be cell-type dependent, so neither mammalian nor invertebrate proteins is optimal in amphibian oocytes. We cloned the X.

Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus.

An isolate of Haemonchus contortus, UGA/2004, highly resistant to benzimidazoles, levamisole, and ivermectin was isolated from sheep at the University of Georgia, and passaged through experimentally infected goats. We measured the expression of twenty-nine mRNAs encoding drug targets and P-glycoproteins (P-gps), comparing the results to a fully susceptible laboratory passaged isolate. Expression levels of some nicotinic acetylcholine receptor mRNAs were markedly different in UGA/2004.

A new homogeneous assay for high throughput serological diagnosis of brucellosis in ruminants.

The control and eradication of brucellosis is highly desirable but heavily resource intensive as high throughput serological testing is required. The aim of this study was to meet the needs of high throughput screening laboratories involved in this process through the development of a new assay. An existing cELISA used for the serodiagnosis of brucellosis in ruminants was converted to an AlphaLISA homogenous proximity based assay.

Low vision service models in Alberta: innovation, collaboration, and future opportunities.

As Alberta's population ages over the next 20 years, the number of older adults experiencing age-related blindness or vision loss is likely to at least double. To prevent a crisis in low vision service provision, we need to build upon, and extend, existing partnerships between the CNIB and ophthalmologists, optometrists, government policy makers, and other service providers. Future service models for low vision rehabilitation should also emphasize interventions such as counselling and peer support that enhance quality of life.