Publications by authors named "Kate Harline"
Background: Live imaging is the gold standard for determining how cells give rise to organs. However, tracking many cells across whole organs over large developmental time windows is extremely challenging. In this work, we provide a comparably simple method for confocal live imaging entire Arabidopsis thaliana first leaves across early development.
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- Heterotrimeric GTP-binding proteins, made up of Gα, Gβ, and Gγ subunits, play a crucial role in regulating various signaling pathways in plants, affecting important traits like seed yield and stress responses.
- Current research indicates that plant G-protein functions may differ from other eukaryotes, potentially being spontaneously active or regulated by more complex mechanisms.
- Understanding these unique biochemical properties of plant G-proteins could lead to new agricultural advancements by allowing for targeted manipulation of these proteins.
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- Modeling is increasingly used in biology for exploring complex questions and guiding experiments, but many biologists lack the necessary literacy in modeling techniques and theory.
- This gap in understanding leads to poor communication and hinders progress in gathering and analyzing data.
- The authors propose a blueprint to help biologists effectively use models, illustrated through case studies in developmental-biomechanics and evolutionary biology, showcasing the versatility of models in biological research.
A new study presents a three-dimensional mechanical model with multiple cell layers to interrogate the flattening of organs during development. This model shows the importance of initial asymmetry and its reinforcement by mechanical feedback within the inner cell walls, not the outer epidermal wall, in guiding organ flattening of organ primordia.
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- Plant disease resistance is influenced by complex genetics, with maize being a key focus due to limited characterization of disease resistance loci.
- Researchers analyzed a nested near-isogenic line library of 412 lines, using genetic tools to identify resistance to northern leaf blight caused by a specific fungal pathogen.
- Their findings linked specific genetic traits to leaf architecture and disease resistance, highlighting the potential for improving crop resilience through genetic research.
Aldehyde dehydrogenases are versatile enzymes that serve a range of biochemical functions. Although traditionally considered metabolic housekeeping enzymes because of their ability to detoxify reactive aldehydes, like those generated from lipid peroxidation damage, the contributions of these enzymes to other biological processes are widespread. For example, the plant pathogen strain DC3000 uses an indole-3-acetaldehyde dehydrogenase to synthesize the phytohormone indole-3-acetic acid to elude host responses.
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