Mass-analyzed velocity map imaging of doubly charged photofragments from C70.

The velocity distributions of the fragments produced by dissociative photoionization of C(70) have been measured at several photon energies in the extreme UV region, by using a flight-time resolved velocity map imaging (VMI) technique combined with a high-temperature molecular beam and synchrotron radiation. Average kinetic energy release was estimated for the six reaction steps of consecutive C(2) emission, starting from C(70)(2+) → C(68)(2+) + C(2) to C(60)(2+)→ C(58)(2+) + C(2). The total kinetic energy generated in each step shows a general tendency to increase with increasing hν, except for the first and fifth steps.

Communication: Mass-analyzed velocity map imaging of thermal photofragments from C60.

The velocity distributions of the fragments produced by dissociative photoionization of C(60) have been measured in the extreme UV region for the first time, by using a flight-time resolved velocity map imaging technique combined with a high-temperature molecular beam and synchrotron radiation. Values of the average kinetic energy release were estimated at six different photon energies with respect to five reaction steps of sequential C(2) ejection, starting from C(60)(2+)-->C(58)(2+)+C(2) to C(52)(2+)-->C(50)(2+)+C(2). The translational temperatures of the fragment ions were found to be lower than those obtained by laser multiphoton absorption of C(60).

Manganese oxide nanoparticle-assisted laser desorption/ionization mass spectrometry for medical applications.

We prepared and characterized manganese oxide magnetic nanoparticles ( =5.6 nm) and developed nanoparticle-assited laser desorption/ionization (nano-PALDI) mass spectrometry. The nanoparticles had MnO and MnO cores conjugated with hydroxyl and amino groups, and showed paramagnetism at room temperature.

Photoabsorption cross section of C70 thin films from visible to vacuum ultraviolet.

Absolute photoabsorption cross sections of C(70) thin films were determined for hv values from 1.3 to 42 eV using photon attenuation. The spectrum showed a prominent peak of 1320 Mb at 21.

[Role of pharmaceutical company pharmacist in provision of drug information for cancer chemotherapy].

Recently, oxaliplatin(L-OHP)and irinotecan hydrochloride hydrate(CPT-11)have gained recognition as key drugs in the treatment of advanced colorectal cancer. In this article, we describe the results of a survey of medical institutions by pharmacists working at a pharmaceutical company. First, questions from medical institutions on L-OHP and CPT-11 were totaled and analyzed.

Novel 3,4-diazabenzotropone compounds (2,3-benzodiazepin-5-ones): synthesis, unique reactivity, and biological evaluation.

Efficient synthesis of 3,4-diazabenzo[b]tropone was first achieved utilizing 4pi-8pi sequential electrocyclic reactions of functionalized benzocyclobutenone derivatives. These compounds are highly electron deficient and readily form amine adducts at ambient temperature. Furthermore, gentle heating resulted in quantitative nitrogen extrusion to produce indenone derivatives.

Relative partial cross sections for single, double, and triple photoionization of C60 and C70.

Partial cross sections for the photoion formation from C(60) and C(70) were determined from the yields of singly, doubly, and triply charged ions which were measured by mass spectrometry combined with tunable synchrotron radiation at hnu = 25-120 eV. The dependence of the detection efficiencies on the mass-to-charge ratio was evaluated by using the formula proposed by Twerenbold et al. Corrections of the detection efficiency were found to be critical for obtaining accurate partial cross sections for photoionization of fullerenes.

Melting and freezing behaviors of prototype ionic liquids, 1-butyl-3-methylimidazolium bromide and its chloride, studied by using a nano-Watt differential scanning calorimeter.

1-Butyl-3-methylimidazolium bromide ([bmim]Br) and its chloride ([bmim]Cl) are representative prototypes of ionic liquids. We investigated the melting and freezing behaviors of [bmim]Br and [bmim]Cl by using a homemade differential scanning calorimeter (DSC) with nano-Watt stability and sensitivity. The measurements were carried out at heating and cooling rates slow enough to mimic quasi-static processes.