Publications by authors named "Katarzyna Sierakowska"

Article Synopsis
  • The study investigates elderly patients (over 80 years old) in Polish ICUs, aiming to understand their clinical features and outcomes.
  • Researchers collected data from 371 patients, comparing frail (CFS > 4) to non-frail patients and assessing mortality rates.
  • Findings indicate higher ICU and 30-day mortality in frail patients, with clinical frailty scale (CFS) and SOFA score being significant predictors of ICU mortality.
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Article Synopsis
  • A study was conducted to evaluate if the tendency to limit life-sustaining treatment (LST) among elderly patients in Poland increased from 2016-2017 to 2018-2019.
  • The research involved analyzing data from two cohorts of critically ill patients aged over 80, finding that the prevalence of LST limitations rose from 16.1% to 20.5% over the years.
  • Although the increase wasn't statistically significant in basic analyses, further investigation showed a stronger inclination to limit LST in the later cohort, along with higher mortality and longer hospital stays for patients with LST limitations.
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The development of artificial intelligence (AI) allows for the construction of technologies capable of implementing functions that represent the human mind, senses, and problem-solving skills, leading to automation, rapid data analysis, and acceleration of tasks. These solutions has been initially implemented in medical fields relying on image analysis; however, technological development and interdisciplinary collaboration allows for the introduction of AI-based enhancements to further medical specialties. During the COVID-19 pandemic, novel technologies established on big data analysis experienced a rapid expansion.

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Inflammation plays a key role in the pathophysiology of organ dysfunction in the critically ill patients and is triggered by an overwhelming host response resulting in the overproduction of various cytokines. Regaining immune homeostasis over the dysregulated immune response through broad removal of cytokines using extracorporeal blood purification therapies has recently gained increasing attention. Nonetheless, many questions remain regarding the appropriate monitoring treatment, its potential risks, and side effects.

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Out-of-hospital cardiac arrest (OHCA) remains a leading cause of global mortality, while survivors are burdened with long-term neurological and cardiovascular complications. OHCA management at the hospital level remains challenging, due to heterogeneity of OHCA presentation, the critical status of OHCA patients reaching the return of spontaneous circulation (ROSC), and the demands of post ROSC treatment. The validity and optimal timing for coronary angiography is one important, yet not fully defined, component of OHCA management.

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For years, the diagnosis of prostate cancer has been understated. Despite the relatively low mortality rate, prostate cancer is still one of the most common neoplasms in men, which proves the need for continuous improvements in the diagnostics of this disease. New biomarkers may address these challenges in the form of extracellular vesicles (EV) secreted by prostate cancer cells.

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Article Synopsis
  • Atrial fibrillation (AF) is a common condition among patients undergoing cardiac surgery, increasing the risk of postoperative arrhythmias and the need for permanent pacemaker (PPM) implantation.
  • A study of nearly 12,000 patients revealed that 2.5% required PPM after valve surgery, with higher rates in certain types of surgeries.
  • Long-term follow-up indicated that PPM implantation did not lead to higher mortality rates, while surgical ablation (SA) was associated with improved survival regardless of PPM status.
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We would like to invite paediatric intensive care units (PICU) to join our multi-center trial concerning patient population < 12 y/o and aiming at: • validation of computed tomography angiography (CTA)/computed tomography perfusion (CTP) tests for brain death/death by neurological criteria (BD/DNC) diagnosis procedures, • validation of duplex Doppler insonation of extracranial segments of the internal cerebral arteries and the vertebral arteries for choosing an optimal time for CTA/CTP testing.

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Background: Data regarding the clinical outcomes of covered stents (CSs) used to seal coronary artery perforations (CAPs) in the all-comer population are scarce. The aim of the CRACK Registry was to evaluate the procedural, 30-days and 1-year outcomes after CAP treated by CS implantation.

Methods: This multicenter all-comer registry included data of consecutive patients with CAP treated by CS implantation.

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