Publications by authors named "Katarzyna Modrzewska"

Article Synopsis
  • The study explored the relationship between nasal carriage of Staphylococcus aureus and superantigens (SAg) with disease activity in patients with granulomatosis with polyangiitis (GPA), involving 150 hospitalized patients from 2009-2016.
  • Results showed SAg present in about 35% of nasal swabs but did not establish a significant correlation with GPA activity, although specific SAg like SED and TSST-1 appeared more frequently in active cases.
  • The use of trimethoprim/sulfamethoxazole treatment was found to be protective, while limited disease (subglottic stenosis) was linked to increased activity, indicating further mechanisms are needed to understand GPA exacerbation
View Article and Find Full Text PDF

Primary pulmonary angiosarcoma is an extremely rare disease. Chest computed tomography demonstrates solitary or multifocal lesions, sometimes associated with ground-glass opacities or pleural effusion. Diagnosis is based on histological examination that reveals spindle-shaped epithelioid cells with positive staining for endothelial markers (factor VIII, CD 31, CD34, Fli-1, Ulex europaeus agglutinin 1, vimentin).

View Article and Find Full Text PDF

Actinomycosis is a rare, chronic infectious disease caused by anaerobic Gram-positive bacteria Actinomyces spp. They induces suppurative inflammation in tissues. They live as commensals in the oropharynx, interstitial tract and genital mucosa, causing almost exclusively endogenic infections.

View Article and Find Full Text PDF

Yellow nail syndrome (YNS) is a condition characterized by yellow-green coloration of nails, respiratory manifestations and lymphoedema. This article presents 52-year-old patient with membranous glomerulonephritis, hospitalized at the National Tuberculosis and Lung Diseases Research Institute in Warsaw, because of suspected allergic aspergillosis. Based on clinical and radiological evaluation the diagnosis of YNS was established.

View Article and Find Full Text PDF

Common variable immunodeficiency is a primary immunodeficiency disease, characterized by hypogammaglobulinemia, low serum immunoglobulin concentrations, and recurrent bacterial infections of the respiratory and gastrointestinal tracts. We report on a 33-year-old patient with suspected sarcoidosis, diagnosed on the basis of an open lung biopsy, who was admitted to the National Tuberculosis and Lung Diseases Research Institute because of severe pneumonia and streptococcal sepsis. During diagnostics based on typical, clinical and laboratory features, CVID was diagnosed.

View Article and Find Full Text PDF