X-ray tomography with multiple ultranarrow cone beams.

Hollow glass microcapillaries or x-ray waveguides very efficiently confine x-rays to submicron or nanospots, which can be used for point projection imaging. However, x-ray beams exiting from such devices have ultranarrow cones that are limited by the critical angle for the total external reflection to a few milliradians. Narrow cone beams result in small fields of view, and the application of multiple-reflection optics to cone beam tomography is challenging.

Biophysical and Biochemical Characteristics as Complementary Indicators of Melanoma Progression.

The multistep character of cancer progression makes it difficult to define a unique biomarker of the disease. Interdisciplinary approaches, combining various complementary techniques, especially those operating at a nanoscale level, potentially accelerate characterization of cancer cells or tissue properties. Here, we study a relation between the surface and biomechanical properties of melanoma cells, measured by mass spectrometry (ToF-SIMS) and atomic force microscopy (AFM).

Grid-enhanced X-ray coded aperture microscopy with polycapillary optics.

Polycapillary devices focus X-rays by means of multiple reflections of X-rays in arrays of bent glass capillaries. The size of the focal spot (typically 10-100 μm) limits the resolution of scanning, absorption and phase-contrast X-ray imaging using these devices. At the expense of a moderate resolution, polycapillary elements provide high intensity and are frequently used for X-ray micro-imaging with both synchrotrons and X-ray tubes.

Defect-Assisted Hard-X-Ray Microscopy with Capillary Optics.

Polycapillary x-ray focusing devices are built from hundreds of thousands of bent microcapillaries that are stacked into hexagonal arrays. We show that intrinsic point defects of the optics (e.g.