Expression of NEAT1, PACERR, and GAS5 circulating long noncoding RNAs can be associated with disease activity in rheumatoid arthritis patients.

Introduction: Long noncoding RNAs (lncRNAs) have long been considered molecular noise within the transcriptome, but over time it has been shown that they perform many important biological functions and are associated with various inflammatory and autoimmune diseases, including rheumatoid arthritis (RA).

Objectives: The aim of this study was to evaluate the association between the circulating lncRNAs and RA activity.

Patients And Methods: The study included 63 patients with well‑established RA (median disease duration of 12 years), at a mean (SD) age of 51.

Placental Cannabinoid Receptor Expression in Preterm Birth.

The cannabinoid receptor (CBR) plays a significant role in oogenesis, pregnancy, and childbirth. It might also play a significant role in preterm birth (PTB). The aim of the study was to investigate the association between the expression of the CBR in the placenta and the incidence of PTB.

Bioleptin as a useful marker of metabolic status in children with diabetes mellitus type 1.

Introduction: The purpose of our study was tomeasure the level of leptin and biologically active leptin (bioLEP) in children with type 1 diabetes, depending on the duration of diabetes and its degree of metabolic control.

Methods: The study included 94 children (58 boys and 36 girls). In a group of children with diabetes, 40 patients were newly diagnosed with type 1 diabetes, 40 children who have diabetes for more than a year (20 with good metabolic control and 20 with poor metabolic control).