Publications by authors named "Katarzyna Chmur"
Article Synopsis
- The crystal structures of two new oxidovanadium(IV) salts were identified, along with their cytotoxic effects on prostate and breast cancer cells.
- Four N-heterocyclic salts showed strong cytotoxic action on both cancerous and normal cells.
- The compounds' effectiveness varied based on the structure of the counterion, with one specific compound demonstrating the highest activity, while another exhibited the lowest toxicity and distinct effects on cell cycle distribution in cancer cells.
In this article, the implications of binding competition of vanadates(V) with dodecyl sulfates for bovine serum albumin on cytotoxicity of vanadium(V) species against prostate cancer cells have been investigated. The pH- and SDS-dependent vanadate(V)-BSA interactions were observed. At pH 5, there is only one site capable of binding ten vanadates(V) ions (logK = 4.
View Article and Find Full Text PDFThe binding interactions of bovine serum albumin (BSA) with tetraphenylborate ions ([B(Ph)]) have been investigated by a set of experimental methods (isothermal titration calorimetry, steady-state fluorescence spectroscopy, differential scanning calorimetry and circular dichroism spectroscopy) and molecular dynamics-based computational approaches. Two sets of structurally distinctive binding sites in BSA were found under the experimental conditions (10 mM cacodylate buffer, pH 7, 298.15 K).
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